Trabalho Apresentado no World Congress of Integrative Medicine & Health – Berlim / 2017

Jacquelyne Motta

Aqui está o resumo do trabalho apresentado no World Congress of Integrative Medicine realizado em Berlim no ano 2017.

Trabalho Apresentado no World Congress of Integrative Medicine & Health

Dieta cetogênica no tratamento de Hemangioma cavernoso em cão.

Jacquelyne Motta, Ana Catarina Valle, Fabíola Donadão

Resumo

Objetivo

O objetivo do presente relato de caso, é verificar a eficácia da dieta cetogênica para o tratamento de Hemangioma cavernoso em abdomem de um cão, como uma terapia alternativa para esse tipo de tumor.

Métodos

Cão da raça Shitzu, 4 anos, foi encaminhado à exame de ultrassonografia abdominal onde foi visualizado formações nodulares hiperecogênicas na região umbilical. Esse paciente foi encaminhado à cirurgia para realização de biópsia com diagnóstico histopatológico de Hemangioma cavernoso. Após três cirurgias sem sucesso, optou-se por utilizar quimioterapia para tentar impedir o crescimento tumoral, também sem sucesso. Iniciou-se então, um programa nutricional com dieta cetogênica na qual os carboidratos são substituídos por gorduras saudáveis e quantidades moderadas de proteína de alta qualidade para metabolizar corpos cetônicos como combustível alternativo à glicose.

Resultados

Durante a terapia dietética, o paciente realizou dieta à base de (gordura + poucos carboidratos + proteína) dieta cetogênica. O paciente foi submetido a novos exames ao longo de 8 meses de tratamento, onde constatou-se que peso corporal foi reduzido em cerca de 10% e não foi detectado crescimento do tumor ao exame ultrassonográfico. O presente relato de caso está em andamento.

Conclusões

Observamos que a dieta cetogênica, pode oferecer mecanismos anti-angiogênicos e pró-apoptóticos, uma vez que as células tumorais têm uma reduzida capacidade de metabolizar esses corpos cetônicos. A dieta cetogênica, pode, nesse sentido, oferecer esperança contra o câncer, tanto para a prevenção como para tratamento.

Ketogenic Diet for Dog with Cavernous Hemangioma

Jacquelyne Motta, Ana Cristina Ladeira de Souza, Ana Catarina Valle, Fabíola Donadão

Summary

The objective of this study is to verify the effectiveness of ketogenic diet as adjunctive therapy in the treatment of abdominal cavernous hemangioma in a dog.

Methods

Abdominal ultrasound results from a four-year old Shih-Tzu showed the formation of hyperechoic nodules in the umbilical region.

The dog went through three surgeries, including surgical biopsy with histopathological diagnosis of cavernous hemangioma. After all unsuccessful attempts, the patient took chemotherapy as an option to stop tumor growth, also without success. As an alternative therapy, a nutritional program with ketogenic diet was adopted.

The ketogenic diet consists in the replacement of carbohydrates by healthy fats, which are converted to ketones, and in the intake of moderate amounts of high quality protein to metabolize ketone bodies as an alternative fuel, when glucose availability is low.

Results

During dietary therapy, the patient was fed ketogenic diet (healthy fat + protein + very few carbohydrates) for a monitoring period of 8 months, while further evaluations were made.

The results showed reduction of about 10% of the body weight, and no tumor growth detected by ultrasonography. This case study is still in progress.

Findings

The ketogenic diet can provide anti-angiogenic and pro-apoptotic mechanisms, suggesting that tumor cells have reduced ability to metabolize these ketone bodies for energy. It can offer hope against cancer, both for prevention and treatment.

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